While the line-up looked solid on paper, the road to Bramham Park was famously bumpy.
Shortly after the first announcement, a major logistical swap saw Feeder and Yeah Yeah Yeahs switch days, a move that sent fans scrambling to reorganise their weekend plans.
The bill also faced a string of high-profile cancellations; Audioslave and The Shins both pulled out, while the emo contingent took a hit when From First to Last (featuring a pre-Skrillex Sonny Moore) and Paramore both withdrew due to their lead singers' throat issues.
Despite the dropouts, the weekend was packed with unique moments, such as Flogging Molly pulling double duty by playing sets in both the punk tent and on the main stage.
For those lucky enough to attend, the price of admission for this slice of music history was just £135 for a weekend ticket or £60 for a day pass; figures that feel like a distant memory in today's touring climate.
So, who were some of the big names to perform at Leeds Festival 2006, and where are they now?
19. The Raconteurs (Radio 1 Stage)
Jack White’s supergroup remains a 'when the stars align' project. While White is currently busy with his solo material, Ticketmaster has listed them for potential 2026 concert activity. | Getty Images
20. Coheed and Cambria (Radio 1 Stage)
The prog-rockers are fully active and hitting the US festival circuit in 2026, with major slots at Welcome to Rockville and Sonic Temple alongside My Chemical Romance. | Getty Images
21. Clap Your Hands Say Yeah (Radio 1 Stage)
Alec Ounsworth continues the project as a solo endeavour. For February 2026, he is performing a unique 'Piano & Voice' tour across North America. | AFP via Getty Images
22. Be Your Own Pet (Radio 1 Stage)
After a 15-year hiatus, the Nashville punks officially reunited in 2022 and released new music in 2023. While they don't have 2026 dates listed yet, they are firmly back together. | Kirsten Barnett
23. Plan B (Radio 1 Stage)
Ben Drew has moved more into film and production in recent years, but his 2006 debut remains a landmark of UK hip-hop. He still makes sporadic live appearances. | Universal Images Group via Getty
24. Maximo Park (Radio 1 Stage)
The Newcastle quintet is celebrating 20 years of A Certain Trigger with a 20th-anniversary tour in February 2026, which includes a highly anticipated stop in Leeds. | Getty Images