Aidan Sezer, the club’s only experienced scrum-half, is ruled out because of injury, alongside forward James Bentley.
In more positive news, winger David Fusitu’a and back-rower James McDonnell could return, but three-quarter Nene Macdonald remains in Australia on paternity leave.
Here’s how Leeds could line up in a game they have to win to keep faint top-six hopes alive.
1. Full-back: Luke Hooley
The Super League rookie has had three good games since first-choice full-back Richie Myler suffered a long-term injury. Photo: Ed Sykes/SWpix.com
2. Wing: David Fusitu'a
Missed last week's defeat at Huddersfield because of a back injury, but has been named in the initial squad for Saturday. Photo: Ed Sykes/SWpix.com
3. Centre:Luis Roberts (no 24)
With Nene Macdonald still in Australia on paternity leave, Roberts is likely to retain his place. Photo: Tony Johnson
4. Centre: Harry Newman
Set for his third comeback game following injury, having got through 80 minutes last week. Photo: Allan McKenzie/SWpix.com
5. Wing: Ash Handley
Rhinos' top try scorer this term, likely to remain in his specialist role. Photo: Alex Whitehead/SWpix.com
6. Stand-off: Rhyse Martin
Morgan Gannon could start at six, but Rhinos might continue with Martin for a second successive game, so they have a more experienced head in the halves. Photo: Ed Sykes/SWpix.com