Aidan Sezer, the club’s only experienced scrum-half, is ruled out because of injury, alongside forward James Bentley.
In more positive news, winger David Fusitu’a and back-rower James McDonnell could return, but three-quarter Nene Macdonald remains in Australia on paternity leave.
Here’s how Leeds could line up in a game they have to win to keep faint top-six hopes alive.
13. Loose-forward Cameron Smith
Had a big game last week and his defence and play-making skills will both be needed on Saturday. Photo: Ed Sykes/SWpix.com
14. Sub: Tom Holroyd
Started last week, but could be among the subs to give Rhinos more size on the bench. Photo: Ed Sykes/SWpix.com
15. Sub: Sam Lisone
Made a considerable impact off the bench at Huddersfield. Photo: Ed Sykes/SWpix.com
16. Sub: James Donaldson
Will be needed to come on as a replacement prop. Photo: John Clifton/SWpix.com
17. Sub: Leon Ruan
The rookie second-rower got a brief run off the bench last week and will probably retain his place. Photo: Allan McKenzie/SWpix.com