Marcelo Bielsa’s men travel to champions Liverpool on Saturday evening for their first top-flight match in 16 years.
But do the bookies believe the Whites’ stay in the top-flight will extend into a second season? Scroll and click through the pages to discover each club’s relegation odds:
13. Leeds United
Odds to be relegated from the Premier League: 4/1 Photo: Michael Regan
14. Brighton & Hove Albion
Odds to be relegated from the Premier League: 10/3 Photo: RICHARD HEATHCOTE
15. Burnley
Odds to be relegated from the Premier League: 11/4 Photo: LINDSEY PARNABY
16. Newcastle United
Odds to be relegated from the Premier League: 2/1 Photo: JAN KRUGER
17. Crystal Palace
Odds to be relegated from the Premier League: 2/1 Photo: Justin Setterfield
18. Aston Villa
Odds to be relegated from the Premier League: 7/4 Photo: Justin Setterfield