With Mikolaj Oledzki returning from long-term injury and James Bentley available following suspension, Smith is set to make at least two changes to a winning team.
They replace James Donaldson and Liam Tindall in the initial 21 and the other change sees Luis Roberts return in place of Jack Sinfield.
It will be tough on whoever gets left out, following last Saturday’s excellent comeback win over Catalans Dragons.
The key calls are probably whether to continue with Rhyse Martin at centre or switch him back to the second-row; if Oledzki returns in the starting side and does Smith go with a specialist hooker, Corey Johnson, on the bench? Here’s how Rhinos could line up.
13. Second-row: Rhyse Martin
Could be the final Leeds appearance for one of the club's best overseas signings, against the club he'll join next season. Photo: Jonathan Gawthorpe
14. Loose-forward: Cameron Smith
The captain has missed just one game, through suspension, this season. Photo: Bruce Rollinson
15. Sub: Jarrod O'Connor
On the verge of completing a second successive ever-present campaign. Photo: Steve Riding
16. Sub: Sam Lisone
Now back on the bench after a spell in the starting 13. Photo: Allan McKenzie/SWpix.com
17. Sub: James Bentley
Might revert to starting second-row next year, but has been going well as a substitute 'middle'. Photo: John Clifton/SWpix.com
18. Sub: James Donaldson
Has given Rhinos excellent service since being discarded by Hull KR six years ago, will be keen to make a big impact in his final regular-season Super League game. Photo: Allan McKenzie/SWpix.com