West Yorkshire Fire Service were called to the fire at The Old Maggot Farm on Stocking Lane just after 5.30am today (Jan 1).
Fire crews from stations at Pontefract, Castleford, Garforth and Normanton were called to the scene and there were seven pumps at the height of the blaze.
Crews remained at the scene this afternoon.
The Old Maggot Farm is 200m from the River Aire and next to Willow Garth nature reserve.
The Environment Agency tweeted earlier today: "Environment Agency officers are currently attending a waste tyre fire and supporting @WYFRS at a site in Knottingley.
"Officers are checking impact on water quality on the River Aire and advising on pollution containment."
West Yorkshire Fire and Rescue Service tweeted just after 7pm today: "Crews from across the service are continuing to fight a tyre fire outside the old maggot farm on Stocking Lane, Knottingley, near the River Aire.
"Local residents are advised to keep doors and windows closed as the service works with the Environment Agency and other partners."