Rhinos will be boosted by the return of half-back Aidan Sezer (groin injury), hooker Kruise Leeming (illness) and second-row James Bentley (suspension), but that means some difficult decisions for coach Rohan Smith.
He has confirmed Sezer will start, so where Richie Myler - who can play at half, full-back or, at a push, as hooker - fits into the team is one of the most intriguing selection posers.
Here's how Rhinos could line up as they bid to end a 10-game losing run against the reigning champions.
1. Zak Hardaker (full-back)
Other options are available, but Hardaker is the man in possession and has gone well so far. Photo: Bruce Rollinson
2. David Fusitu'a (wing)
Will get an opportunity to continue his strong recent form. Photo: Bruce Rollinson
3. Harry Newman (centre)
Made his comeback as a substitute and with two more weeks' training under his belt, is ready to start. Photo: Jonathan Gawthorpe
4. Liam Sutcliffe (centre)
Likely to continue in his favoured role. Photo: Bruce Rollinson
5. Ash Handley (wing)
Injuries permitting, a guaranteed starter on the left-flank. Photo: Jonathan Gawthorpe
6. Blake Austin (stand-off)
Has some competition now, but is in good form. Photo: Bruce Rollinson