Three of the side which faced St Helens last week - centre Harry Newman, scrum-half Aidan Sezer and stand-off Morgan Gannon - picked up long-term injuries, forward Zane Tetevano is ill and winger David Fusitu’a and prop Sam Lisone remain on the casualty list.
Much will depend on whether stand-off Blake Austin and second-row James Bentley are fit enough to return after two weeks out of the team.
The side looks a lot more experienced with them in it. If they, or anyone else, don’t make it, at least two of Luis Roberts, Luke Hooley, Leon Ruan and Alfie Edgell - with a total of six Betfred Super League appearances between them, five of those by Roberts - will get a shot.
Assuming everyone in the 17 is fit, probably only five of the 13 starting positions are set in stone. Here’s how Rhinos could line up.
1. Full-back: Ash Handley
Was named on a wing last week, but made a quick shift to full-back and did a good job. Luke Hooley is an alternative if Handley is needed in the three-quarters. Photo: Allan McKenzie/SWpix.com
2. Wing: Liam Tindall
Was 18th man last week, but has big-game experience and can be relied upon to come in and do a good job, though Luis Roberts is an alternative option. Photo: Allan McKenzie/SWpix.com
3. Centre: Nene Macdonald
One of Rhinos' form players, could be on a wing, but centre seems more likely. Photo: Allan McKenzie/SWpix.com
4. Centre: Rhyse Martin
Rhinos are short in both his positions, centre and second-row, but Smith may want Martin to add some experience in the three-quarters. Photo: Allan McKenzie/SWpix.com
5. Wing: Derrell Olpherts
Did enough last week to retain his place and will want a big game against his previous club. Photo: Allan McKenzie/SWpix.com
6. Stand-off: Blake Austin
Will play if he has fully recovered from his calf muscle injury. Photo: Allan McKenzie/SWpix.com