The 37-year-old retired from playing at the end of the 2017 season, winning an eighth Super League Grand Final in his last game.
Breaking the news, Burrow said: “Regrettably, today I am confirming that I have been diagnosed with motor neurone disease.
“I would like to thank everyone for the support I have received already since being given my diagnosis.
“I know I have a big challenge in front of me, but knowing that I have the love and support of so many people will give me inspiration and strength.”
The community took to social media to share their support for the player.
Glen Hodgson said: "Not my idea but - I know it’s not Leeds united but I reckon our next home game on the 7th minute we chant a song for Rob Burrow he was Leeds his whole career, let’s show him and his family all of our support."
Tracy Hogan said: "Oh no. Rob was such a star when my nephew died and wrote such a lovely card to my brother. So very, very sad. Such a lovely bloke and such a horrible disease."
Scott Lee said: "Very sad news for a cracking player,hope Rob & his family get all the support they need at this difficult time."
Darrell Close said: "So sorry to hear this sad news. Keep fighting rob your a winner."
Emma Holland said: "God help Rob and his family. The road is long the mountain high but the support and love is mighty we are all behind you Rob 110% sending much love and prayers from Northern Ireland."
Julie Pennington said: "Such sad news for Rob and his family. Much love from your Rugby family."
Christian Hobson said: "Arguably the finest player Leeds ever produced..... so incredibly sad."
Steven Walker said: "Not a Rhinos fan but awful devasting news heart like a Lion that lad good luck Rob."
Tracey Mclauchlan said: "Loved watching him play. Sad news but a man with spirit and fight in him, I’m sure he won’t be beaten!"
Pauline Deegan said: "This is so awful my fav player so courageous was he amazing rugby player tragic news."
Pauline Gorman said: "What terrible news to receive at this time of year.. and at his age too, what a legend he is and what a talent he has on the rugby pitch, he has and will continue to be a great inspiration to the younger generations for many years to come.... sending him my prayers thoughts and hugs and wish him a Merry Christmas and hope he has a fantastic New Year with his friends and family, who I’m sure will give him all the love and support he will ever need in the months and years to come!!!"
Peter Ward said: "Sad to see a man so fit starting with this.Saw the interview on the TV such admiration for this giant all he could say was thank you to everybody who helps him."