The Whites travel to take on Pep Guardiola's reigning English champions in midweek action.
City sit top of the pile heading into the festive period with a one point advantage over Liverpool after 16 games following Saturday's victory over Wolves on home soil.
Leeds, meanwhile, are 15th in the standings following a late defeat at third-placed Chelsea in the capital.
Bielsa is unable to welcome back any of his squad for the top flight encounter. Kalvin Phillips, Liam Cooper and Patrick Bamford remain out with hamstring problems.
Robin Koch has returned to training but isn't available following his absence since August while Pascal Struijk (foot) and Rodrigo (heel) continue to recover in the treatment room.
"No new injuries from the last game, no new players returning and I can't clarify anything on Kalvin at the moment," said Bielsa during his pre-match press conference.
"At the moment I have no precise news over his hamstring over his shoulder."
Joe Gelhardt' s impact from the bench after scoring at Chelsea with his first touch is likely to be the dominating decision for Bielsa.
Leeds began the game at Stamford Bridge with two wide forwards in Raphinha and Dan James rather than a central focal point leading the line.
Here, we take a look at how the Whites could shape up against Guardiola's side...

7. Harrison - LW/LWB
A number of players in the line-up played in a hybrid role at the weekend. He'll be required down the left hand side, you'd think. First time he can face his former side, too. Photo: Getty

8. Shackleton - RWB/RW
Similar to Harrison on the opposite flank, played a hybrid role mixed between wing-back and right winger. One yellow away from a ban. Photo: Getty

9. Roberts - AM
Has shown plenty of craft in recent weeks and provided a quality assist for Gelhardt at the weekend. Also one booking from a ban. Photo: Getty

10. Raphinha - RW/ST
Almost a wide right forward against Chelsea. Another goal and Leeds will again need him for his pace and craft vs City. Needs to avoid a yellow card as well. Photo: Getty

11. James - ST/LW
Certainly played more central in the first half than Raphinha, but it was a similar job as a left wide forward. Pace may be a huge bonus for Leeds against City, he's got plenty. Photo: Getty

