The Whites have been hit by another spate of injuries ahead of this weekend's trip to the capital to take on the Blues.
Full-back Luke Ayling and striker Patrick Bamford made a long-awaited return to the squad for last weekend's 2-2 draw with Brentford at Elland Road.
However, Bamford has now suffered a hamstring problem which accompanies both Kalvin Phillips and Liam Cooper who both hobbled off against the Bees with the same issue.
No timeframe has been put on any of those injuries but the latter two are expected to be out for an extended period.
Attacker Rodrigo has also been sidelined in recent days in an attempt to rest a heel issue - medical staff at Thorp Arch have recommended immediate rest in a bid to solve the problem.
Robin Koch, who has been recovering from a long-term hip and pelvic issue, will return to training this weekend after being ill for the last week and is also not expected to feature.
"Things happen to us, but these things also happen to our opponents," Bielsa said of the recent injury problems in LS11.
"We’ll not find the difficulties a justification, not because it’s a method, but because I feel that way. To say that the difficulties mean that their performance decreases, from my point of view that is just choosing the easiest path."
Chelsea have opted for a one-man forward line this term under Thomas Tuchel which should see Leeds settle into a 4-1-4-1 formation at Stamford Bridge.
Here, we take a look at how the Whites could line-up in London amid more injury woes...
7. Dallas - CM
Pick a position and Dallas will play there. At Chelsea you'd think he'll be required in the engine room now Ayling is back. Photo: Getty
8. Klich - AM
Struggling for form but Bielsa will be hoping he can play his way into some. Leeds are thin on the ground and will need his energy and craft. Photo: Getty
9. James - LW
Up and down form wise. He has shown flashes of what he can do, Leeds need him to start producing a little more to lessen the load on the opposite flank. Photo: Getty
10. Raphinha - RW
The star man. Could do with some more contributions from around him. Leeds will need him on form at Chelsea. Photo: Getty
11. Roberts - ST
A goal last week should give him the world of confidence. He gives Leeds more bite as a No 9, which James could also play. He has had an impact in the last few games, Leeds will need it again.