Head coach Marcelo Bielsa has two main new injury concerns but also one Whites star back available to return to the fold.
Lee Sobot takes a look at a predicted line-up for the clash against Monday night's visitors.
7. Mateusz Klich (CM)
Earned praise from no less than Robert Lewandowski after his efforts with Poland during the October international break and one of the first names on the Whites team sheet in centre-midfield. A vital cog. Photo by Paul Ellis - Pool/Getty Images.
8. Helder Costa (RW)
Bielsa has more options out wide after the arrival of Raphinha from Rennes and considering Ian Poveda's progress. Bielsa says Raphinha has instantly adapted but Costa should still start on the right. Photo by Paul Ellis - Pool/Getty Images.
9. Jack Harrison (LW)
Ineligible to face parent club Manchester City before the break and replaced by Gjanni Alioski but has been in fine form and looks certain to come straight back in on the left flank. England call at some point? Photo by Shaun Botterill/Getty Images.
10. Rodrigo (ACM)
Tyler Roberts had been starting at no 10 in the absence of Pablo Hernandez who is now back from injury. But Rodrigo has been excellent off the bench in the 10 role for Leeds and might well now start there. Photo by Laurence Griffiths/Getty Images.
11. Patrick Bamford (ST)
Another with outside England hopes, but the bread and butter is with Leeds and Bamford is thriving in the lone striker role. All set to seek additions to his tally of three for the season already. Photo by Jason Cairnduff - Pool/Getty Images.