The Whites head into the game still looking for their first win of the Premier League season, after having to settle for two draws and a loss in their opening three matches.
Writing his weekly predictions piece for BBC Sport, pundit and broadcaster Mark Lawrenson gave his verdict on the Whites' big clash against the Red, and predicted that the visitors - his former side - will emerge 2-1 winners.
Expanding on his choice, the 64-year-old contended: “Leeds have stuttered a little bit so far this season, but I think that's all it is. I don't see them struggling, put it that way.
“There are still lots of positives about the way Marcelo Bielsa's side play, but they are still easy to get at which is something I thought they would change.
“That hasn't happened, which is why I am going with Liverpool. The Reds will get plenty of opportunities in front of goal.”
Meanwhile, Lawro's prediction opponent for the week, The Vaccines frontman Justin Young, backed the Reds secure a 2-0 victory, and contended: “This should be a good, open game but Liverpool should win it.”
The last time the Whites faced the Reds, back in April, Bielsa's side left it late to earn a 1-1 draw at Elland Road, with £18m defender Diego Llorente equalising in the 87th minute to cancel out Senegalese sensation Sadio Mane's first half goal.
We’ve gathered the best of today's Premier League speculation below…

. BURNLEY, ENGLAND - AUGUST 14: A general view of the Premier League Nike Flight match ball prior to the Premier League match between Burnley and Brighton & Hove Albion at Turf Moor on August 14, 2021 in Burnley, England. (Photo by Nathan Stirk/Getty Images)
Premier League Nike Flight match ball. (Photo by Nathan Stirk/Getty Images) Photo: Nathan Stirk

1. Diakhaby set to leave
Valencia “plan to sell” Mouctar Diakhaby during the upcoming winter transfer window. Newcastle United and Leicester City have both been linked. (Deporte Valenciano) (Photo by Aitor Alcalde/Getty Images) Photo: Aitor Alcalde

2. Potter in Gunners' sights
Graham Potter and Thomas Frank are emerging as potential head coaching candidates for Arsenal if, and when, they decide to move on from Mikel Arteta. (TEAMtalk) (Photo by Steve Bardens/Getty Images) Photo: Steve Bardens

3. Wallace in demand
Newcastle United, Celtic, Rangers, and West Ham are all keeping tabs on Millwall talent Jed Wallace, with his contract set to expire next summer. (Football League World) (Photo by Jacques Feeney/Getty Images) Photo: Jacques Feeney

4. Levy eyes up Rudiger
Tottenham Hotspur chairman Daniel Levy is ready to explore the possibility of bringing Chelsea centre-back Antonio Rudiger to the club. (Express) (Photo by Alexander Hassenstein/Getty Images) Photo: Alexander Hassenstein

5. Everton plan to rekindle Maitland-Niles interest
Everton are planning to revive their attempts to sign Arsenal's Ainsley Maitland-Niles in January. (ESPN) (Photo by Lynne Cameron - Pool/Getty Images) Photo: Pool

6. Liverpool in Coman hunt
Liverpool are in the hunt to sign Bayern Munich ace Kingsley Coman, with the winger thought to be closing in on an exit from the Bavarian giants. (Le 10 Sport) (Photo by FRANCK FIFE/AFP via Getty Images) Photo: FRANCK FIFE