Leeds head coach Marcelo Bielsa will again be without playmaker Pablo Hernandez as he recovers from his groin strain while Manchester City loanee winger Jack Harrison is also forbidden from playing against his parent club. This is how we think the Whites will line-up.
1. Illan Meslier (GK)
Superb in last weekend's 1-0 victory at Sheffield United and now set to attempt to keep out Raheem Sterling and Kevin De Bruyne and co. At least there's no Sergio Aguero or Gabriel Jesus. Photo by OLI SCARFF/POOL/AFP via Getty Images.
2. Luke Ayling (RB)
Part of a back three against the Blades but looks set to return to his more natural right-back role with City likely to play one up front, probably Sterling with Aguero and Jesus both out. Photo by Laurence Griffiths/Getty Images.
3. Liam Cooper (CB)
United's captain is now a double centurion for the Whites and appearance no 201 for the club is all set to come against City at the heart of the Leeds defence. Photo by Oli Scarff - Pool/Getty Images.
4. Robin Koch (CB)
Excellent against the Blades in still only his third outing for the Whites. New signing Diego Llorente should now be more than ready but surely it will be Cooper and Koch starting at centre-back. Photo by Shaun Botterill/Getty Images
5. Stuart Dallas (LB)
Picked out for high praise from Darren Fletcher on Match Of The Day 2 after his outing at Bramall Lane in midfield and now likely to be back in the left back role as part of a 4-1-4-1. Photo by Laurence Griffiths/Getty Images.
6. Kalvin Phillips (CDM)
United's Yorkshire Pirlo was handed his second call-up to Gareth Southgate's England squad this week and now set for a fascinating battle against De Bruyne from the holding midfield role. Photo by Oli Scarff - Pool/Getty Images.