Whites head coach Marcelo Bielsa held his pre-match press conference on Thursday lunch-time and provided his latest team news.
Bielsa revealed that some players coming back from injury would play for United's under-23s on Friday and record signing Rodrigo then came through 45 minutes in the victory against Wolves under-23s, scoring a brace.
Bielsa was unable to guarantee when the likes of Kalvin Phillips, Jamie Shackleton and Pascal Struijk would be back.
With that in mind, this is how we think Leeds will start out in their latest visit to the capital.
7. CM - Stuart Dallas
Play him where you like. And this time it could be centre midfield for the Northern Ireland international if Phillips, Struijk and Shackleton don't make it. Otherwise might be back at left back. Photo by Michael Regan/Getty Images.
8. RW - Raphinha
Even Raphinha could not sparkle against Villa but he's quickly become one of the first names on the team sheet and certain to start out wide, just a case of which side. Photo by Naomi Baker/Getty Images.
9. LW - Jack Harrison
Benched for Saturday's hosting of Villa but his replacement Helder Costa did not particularly excel and Harrison might well find himself back in the side. Photo by Alex Pantling/Getty Images.
10. ACM - Tyler Roberts
Handed a chance as United's no 10 of late in the absence of Rodrigo but it could be a close call as to who starts in the position against West Ham with Pablo Hernandez the obvious alternative. Photo by Catherine Ivill/Getty Images.
11. ST - Patrick Bamford
United's no 9 is enjoying a fantastic season and will clearly be leading the line as he looks to add to his tally of 13 goals for the campaign so far. Photo by Mike Egerton - Pool/Getty Images.