The Whites head into the game still looking for their first win of the Premier League season, after having to settle for two draws and a loss in their opening three matches.
Writing his weekly predictions piece for BBC Sport, pundit and broadcaster Mark Lawrenson gave his verdict on the Whites' big clash against the Red, and predicted that the visitors - his former side - will emerge 2-1 winners.
Expanding on his choice, the 64-year-old contended: “Leeds have stuttered a little bit so far this season, but I think that's all it is. I don't see them struggling, put it that way.
“There are still lots of positives about the way Marcelo Bielsa's side play, but they are still easy to get at which is something I thought they would change.
“That hasn't happened, which is why I am going with Liverpool. The Reds will get plenty of opportunities in front of goal.”
Meanwhile, Lawro's prediction opponent for the week, The Vaccines frontman Justin Young, backed the Reds secure a 2-0 victory, and contended: “This should be a good, open game but Liverpool should win it.”
The last time the Whites faced the Reds, back in April, Bielsa's side left it late to earn a 1-1 draw at Elland Road, with £18m defender Diego Llorente equalising in the 87th minute to cancel out Senegalese sensation Sadio Mane's first half goal.
We’ve gathered the best of today's Premier League speculation below…

. BURNLEY, ENGLAND - AUGUST 29: Marcelo Bielsa, Manager of Leeds United signs an autograph ahead of the Premier League match between Burnley and Leeds United at Turf Moor on August 29, 2021 in Burnley, England. (Photo by Jan Kruger/Getty Images)
Marcelo Bielsa, Manager of Leeds United. (Photo by Jan Kruger/Getty Images) Photo: Jan Kruger

1. Willock wants PL move
QPR’S Chris Willock is dreaming of joining his brother Joe in the Premier League. The latter currently plays for Newcastle United. (The Sun) (Photo by Jacques Feeney/Getty Images) Photo: Jacques Feeney

2. Luiz signs new deal
Former Arsenal defender David Luiz has signed a two-season deal worth £52,500-a-week at Brazilian side Flamengo. (Goal) (Photo by Mike Hewitt/Getty Images) Photo: Mike Hewitt

3. Hammers want Preston sensation
West Ham have set their sights on Preston North End midfielder Lewis Leigh. Everton are also keen on the teenager. (Football Insider) (Photo by Charlie Crowhurst/Getty Images) Photo: Charlie Crowhurst

4. Real lead Pogba race
Real Madrid are in pole position to snap up Paul Pogba from Manchester United for free next summer. (Mundo Deportivo) (Photo by FRANCK FIFE/AFP via Getty Images) Photo: FRANCK FIFE

5. Ramsey could leave in January
Aston Villa will revisit sending Aaron Ramsey out on loan in January, having kept the young hotshot at the club following internal discussions this summer. (The Athletic) (Photo by Lewis Storey/Getty Images) Photo: Lewis Storey

6. Phillips opens up on Ward-Prowse snub
Kevin Phillips claims James Ward-Prowse may have snubbed a move to Aston Villa after they sold Jack Grealish to Manchester City. (Football Insider) (Photo by Ian MacNicol/Getty Images) Photo: Ian MacNicol