Marcelo Bielsa will be forced into at least one change for the clash with the Foxes after defender Diego Llorente was again sidelined through injury.
The Spain international has suffered rotten luck since joining the club in the summer and limped off in the opening stages at Newcastle United in midweek during his first start for the club.
United's boss also has a decision to make in midfield, where he made the shock decision to drop Mateusz Klich and start Stuart Dallas in the 2-1 win over the Magpies.
Could the Pole return? Might Dallas move to left-back and Gjanni Alioski drop to the bench?
Brendan Rodgers usually opts for one up front, which would mean Bielsa would opt for his favoured 4-1-4-1 formation.
Here's how we think Leeds may line-up at the King Power stadium which, as ever, could be interchangeable into a 3-3-1-3 if required... let us know your thoughts and how you'd line-up this weekend.
1. GK - Meslier
Bielsa's number one. He returned last time out and should keep his spot between the sticks.
2. RB - Ayling
With Llorente missing he could move into the middle, but Leeds gain much more going forward when he's in his natural position.
4. CB - Struijk
Had to come on early against Newcastle in midweek and did a grand job. Should keep him in the side with injuries aplenty, providing Bielsa was happy. The first change.
5. LB - Dallas
A return to left-back could be preferable. He finished the game in midweek here, after Alioski was replaced by Klich.
6. CDM - Phillips
One of the first names on the team sheet. He's going to have a job on trying to contain James Maddison.