Jesse Marsch's side have not played since the 3-0 win at Watford on Saturday, April 9 but a run of 15 days without a game will be followed by the club's latest test in the capital against Patrick Vieira's Eagles.
The Whites were due to face Chelsea at Elland Road last weekend but the game was postponed due to the Blues' involvement in the FA Cup.
For Leeds, the 15 days off will have provided an opportunity to work on the fitness of either injured or recently-returned players, including England international midfielder Kalvin Phillips.
The Yorkshire Pirlo made his second appearance since re-appearing from a four-month absence due to a hamstring injury when coming on as a second-half substitute in the win at Watford.
Marsch had five players missing through injury for the clash against the Hornets, Adam Forshaw, Junior Firpo and Jamie Shackleton sidelined in addition to longer term absentees Patrick Bamford and Tyler Roberts.
Sixteen days later, this is how we think Marsch's side will line up against the Eagles in Monday night's 8pm kick-off.
7. CM - Mateusz Klich
Robin Koch, Mateusz Klich or Adam Forshaw are the three main choices to partner Phillips in midfield assuming that Phillips starts and that Forshaw is recovered from the calf strain that forced him out at Watford. It might be that Klich gets the nod. Photo by Stu Forster/Getty Images.
8. RW - Raphinha
The Brazilian's tenth goal of the season put Leeds on their way to victory at Watford and Raphinha now has six more games to further boost an impressive tally that also features three assists. Photo by George Wood/Getty Images.
9. LW - Jack Harrison
Harrison's strike completed United's 3-0 win at Watford and the winger has now netted a goal in each of his side's last three games. Dan James is the other main option on the left - but he may once again be used elsewhere. Photo by George Wood/Getty Images
10. ST - Rodrigo
The record signing is thriving under Marsch and bagged his sixth goal of the season in the win at Watford. A banker to start in current form. But who partners him? Photo by George Wood/Getty Images.
11. ST - Dan James
Marsch is clearly very keen on Joe Gelhardt who was being considered as a starter at Wolves but then had a series of minor setbacks. It could be a close call but perhaps James will again lead the line to start with, Joffy then coming on off the bench. Photo by George Wood/Getty Images.