Both sides are still seeking their first victory of the 2021-22 top-flight campaign and Leeds will be looking to bounce back from Sunday's 3-0 reverse at home to Liverpool.
The Whites lost Diego Llorente to injury against the Reds as part of a contest in which fellow centre-back Pascal Struijk was shown a straight red card, for which he is now serving a three-game ban.
Another centre back, Robin Koch, has also been out injured with a pelvic issue whilst Adam Forshaw missed the Liverpool game with a muscular injury.
Whites head coach Marcelo Bielsa confirmed at Thursday's pre-match press conference that Forshaw, Koch and Llorente would all miss the trip to St James' Park, in addition to the banned Struijk, and this is how we think the Whites will line up.
Another centre back, Robin Koch, has also been out injured with a pelvic issue whilst Adam Forshaw missed the Liverpool game with a muscular injury.