While fans will no doubt be keeping a close eye on the likes of Kalvin Phillips and Diego Llorente, the first Whites player to get their campaign underway will be Wales' Tyler Roberts, who could feature against Switzerland on Saturday.
And the attacker sees plenty of similarities between his international and club sides.
"We are all just humble people," said Roberts, asked about comparisons between the current Wales side and the class of 2016 on The Beautiful Game Podcast.
"We all enjoy just going there and just being with each other.
"We do a lot of team stuff together, quizzes and all of that so it's always a good vibe to be fair.
"Because of that culture, that just gets taken onto the pitch and it has shown with some of the results we have been getting and the teams that we have been facing.
"These last few years have been crazy because Leeds and Wales have just been exciting, both teams. I definitely feel that.
"I still think we have got a great chance to be honest.
"It's a group where you are not looking at it like this is going to be a madness because everyone is just cold and everything.
"But I think we definitely look at that group and have got a chance of getting through.
"It's a tournament where many people don't get these chances so if you get a chance to play in it you are just buzzing about it."
We’ve gathered the best of today’s Premier League transfer speculation below...
1. Armstrong set for Toon reunion?
Newcastle United looks the likely destination for Adam Armstrong this summer. (Football League World) (Photo by Nathan Stirk/Getty Images)
Photo: Nathan Stirk
2. Mac Allister staying put
Brighton midfielder Alexis Mac Allister will not be moving to Atletico Mineiro this summer, with the Brazilian side's manager seemingly 'angry' at the suggestion. (Galotube) (Photo by Naomi Baker/Getty Images)
Photo: Naomi Baker
3. Grimes in demand
Newcastle United and Southampton are monitoring Matt Grimes’ situation at Swansea City. (Various) (Photo by Alex Burstow/Getty Images)
Photo: Alex Burstow
4. Burnley bid for Collins
Stoke City defender Nathan Collins is said to be the subject of a new £12m bid from long-term admirers Burnley, with the Clarets hopeful that their improved offer will be accepted. (The Sun) (Photo by Alex Davidson/Getty Images)
Photo: Alex Davidson