The Whites slumped to a 2-0 defeat against Brighton last weekend, slipping out of the top half as a consequence of that result, but will be hoping to bounce back against Spurs.
As for the north Londoners, they will know that anything other than a win will seriously dent their hopes of a top four finish and Champions League football next term.
Speaking ahead of the crucial game, Leeds boss Marcelo Bielsa admitted that he had a tough decision to make over who will start at the heart of defence.
He said: "Pascal [Struijk] and Llorente have shown that they can live up to the level that the previous people who have played in this position were playing at.
"But as you well know, there are other factors that are taken into consideration when you look at each game.
"And in any case what I always consider is what is best for the team and what is best for each player that participates because there is nothing more important than to look at the participation of each player.
"Every time you take a decision you don't only think about the good of the team, you consider each individual.
"Being a starter doesn't just generate a hierarchy within the players available so it doesn't favour any player to be in a starting position if they are not in conditions to respond at their best level."
We've gathered the best of the rest of today's Premier League transfer speculation below...

7. Tagliafico wants challenge
Leeds United target Nicolas Tagliafico has admitted that he would be keen on a summer move. The Ajax defender said: “I’m not going to lie to you, I would love to move to a more challenging league". (Radio Marca) (Photo by Peter Dejong - Pool/Getty Images) Photo: Pool

8. Merino eyed up by Barca
Mikel Merino could replace the legendary Sergio Busquets at Barcelona three years after Newcastle United sold him to Real Sociedad. (Mundo Deportivo) (Photo by Fran Santiago/Getty Images) Photo: Fran Santiago

9. Leeds confident over De Paul deal
Leeds United are confident Rodrigo De Paul can be signed this summer for less than the £37 million Udinese demanded for the player back in 2020. (Football Insider) (Photo by Maurizio Lagana/Getty Images) Photo: Maurizio Lagana

