Dan James heads four Leeds United players starting on busy evening of internationals for Whites
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Third-placed Wales and second-placed Czech Republic are both on seven points in Group E, nine points behind runaway leaders Belgium.
The Czechs occupy the group's play-offs qualification spot on goal difference but Wales have a game in hand.
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Hide AdJames, who Leeds signed from Manchester United this summer, looks set to partner Cardiff City striker Kieffer Moore in a front two for Rob Page's side.
As part of a busy evening of internationals, Whites trio Illan Meslier, Kristoffer Klaesson and Morecambe loanee Alfie McCalmont were all handed starts on Friday for their respective under-21s Euros qualifiers.
Leeds no 1 Meslier started in goal for France under-21s at home to Ukraine whilst Meslier's understudy Klaesson lined up between the sticks as Norway's under-21s took on hosts Croatia.
McCalmont also started for Northern Ireland's under-21s in their qualifier in Russia.
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