Brazilian star winger Raphinha missed last weekend's clash at Tottenham due to being ill whilst record signing Rodrigo sat out the contest due to a minor foot problem.
Junior Firpo also returns to the starting line up having made his comeback after a recent muscular injury as a second-half substitute in Sunday's 2-1 defeat at Tottenham.
Gelhardt, Mateusz Klich and Pascal Struijk are the three players to drop out of the side and on to the bench which also includes Jamie Shackleton who is back available after a recent setback.
Patrick Bamford (ankle), Luke Ayling (knee) and Robin Koch (pelvis) remain out but Ayling is likely to play for United's under-23s on Monday night in the Premier League Two Division One clash at Manchester City.
Whites head coach Marcelo Bielsa said at Thursday's pre-match press conference that Bamford and Koch were in the final period of their recoveries.
Brighton boss Graham Potter has also made three changes to his side.
Goalkeeper Robert Sanchez is back from suspension and replaces Jason Steele in goal whilst Joel Veltman and Neal Maupay also come into the XI as Shane Duffy and Adam Lallana drop out.
Brighton: Sanchez, Veltman, Dunk, Webster, Lamptey, Bissouma, Gross, Cucurella; Moder, Trossard, Maupay. Subs: Steele, Mac Allister, Mwepu, Lallana, March, Duffy, Locadia, Richards, Sarmiento.
Leeds United: Meslier, Dallas, Cooper, Llorente, Firpo, Phillips, Forshaw, Raphinha, James, Harrison, Rodrigo. Subs: Klaesson, Struijk, Cresswell, Shackleton, McCarron, Jenkins, Klich, Roberts, Gelhardt.
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Thank you Laura Collins