The crash has happened on the westbound carriage between junction 23 and junction 22.
A spokesperson from Highways England said: “The M62 in West Yorkshire is experiencing severe delays westbound between Junction 23 and Junction 22 due to an incident involving a HGV and a caravan which has blocked the carriageway.
“Highways England Traffic Officers are currently on scene assisting West Yorkshire Police & Emergency Services.
“Road users may wish to consider alternative routes and are advised to allow extra time for their journey.”
One lane of the motorway has now re-opened.