Head coach Marcelo Bielsa held his pre-match press conference on Thursday morning and delivered updates on the conditions of recent injuries Kalvin Phillips, Raphinha and Helder Costa as well as captain Liam Cooper who is back from suspension.
Leeds will be looking to bounce back from last Saturday's 2-0 defeat at Brighton and this is how we think the Whites will line up.
. Leeds United will face Champions League-chasers Tottenham Hotspur next
DECISONS: Whites head coach Marcelo Bielsa, above, has plenty to ponder with captain Liam Cooper back from suspension but Kalvin Phillips and Raphinha facing fitness battles. Photo by Peter Powell - Pool/Getty Images.
. Illan Meslier (GK)
The impressive French stopper is a banker to start in goal. Photo by PAUL ELLIS/POOL/AFP via Getty Images.
. Luke Aying (RB)
Looks a certainty to start at right back as part of a Whites back four against Tottenham's lone striker Harry Kane but will vice-skipper Ayling have the captain's arm band with Cooper back? Photo by Alex Pantling/Getty Images.
. Liam Cooper (CB)
Back available having served a three-game ban for his straight red card in the 2-1 win at Man City. Tough on whoever drops out but Cooper would seem likely to come back into the team to face Kane. Photo by Stu Forster/Getty Images.
1. Illan Meslier (GK)
The impressive French stopper is a banker to start in goal. Photo by PAUL ELLIS/POOL/AFP via Getty Images.
2. Luke Aying (RB)
Looks a certainty to start at right back as part of a Whites back four against Tottenham's lone striker Harry Kane but will vice-skipper Ayling have the captain's arm band with Cooper back? Photo by Alex Pantling/Getty Images.
3. Liam Cooper (CB)
Back available having served a three-game ban for his straight red card in the 2-1 win at Man City. Tough on whoever drops out but Cooper would seem likely to come back into the team to face Kane. Photo by Stu Forster/Getty Images.
4. Diego Llorente (CB)
Llorente's early injury woes appear firmly behind him and the Spanish international looks the most likely centre-back out of himself and Pascal Struijk to keep their place in defence if Cooper starts. Photo by LEE SMITH/POOL/AFP via Getty Images.
5. Gjanni Alioski (LB)
Subbed at the break against Brighton after a torrid first half and Stuart Dallas might well move to left back but Dallas has been thriving in midfield meaning that Alioski may keep his place - to face Gareth Bale. Photo by PAUL ELLIS/POOL/AFP via Getty Images.
6. Robin Koch (CDM)
Kalvin Phillips clearly starts at CDM when fit but Phillips is being evaluated on a daily basis after picking up a knee injury. Assuming he doesn't make it, Koch or Struijk will likely be in the holding midfield role. Photo by PAUL ELLIS/POOL/AFP via Getty Images.