It follows the death of George Floyd in Minneapolis, USA, who died after a police officer restrained him by kneeling on his neck.
Last week, a joint protest was held in Millennium Square with Black Voices Matter.
The socially-distant demonstration is being held in Hyde Park and begins at 2pm.
Organisers expect more than 2,000 people to fill the park.
When is it?
It is being held on Sunday, June 21.
It begins at 2pm.
Entrance into the demonstration begins from 1.30pm.
It is set to finish at 4pm.
What will be involved?
Organisers said that plans include a line-up of speakers.
A mass kneel in remembrance of the many Black lives that have been lost will also take place.
What are the safety rules in place?
Protesters will have to remain socially-distant.
An entry system will be set up to stagger arrivals into the park.
Once on site, volunteers will assist with directing people to clear spaces, ensuring attendees keep to social distancing guidelines of at least 2 meters between different households.
Demonstrators must bring a face mask and hand sanitiser.
Why are people protesting?
Thousands of people across the UK have turned out for anti-racism protests in major cities.
Protests began in the US after a video emerged of Mr Floyd, 46, being arrested on May 25 in Minneapolis, USA.
Phone footage showed him gasping that he could not breathe during the arrest by four officers.
They have since been charged over the death, which sparked days of protest in the US and Black Lives Matter (BLM).
Marvina Newton from Black Lives Matter Leeds said: "We come together to unite as a city and a nation to fight racism. No longer will we be silent because silence is consent. We aim to create a network to ensure that black lives matter and that power is share equally with black communities in order to dismantle systemic racism in our city and beyond."
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