West Yorkshire Police said road closures had been put in place from Pontefract Lane to the area near the Crooked Billet Inn.
The 33-year-old motorcyclist who was involved in the collision was taken to Leeds General Infirmary with life threatening injuries.
Police are now appealing for any witnesses to the incident to contact them.
Police constable James Farrar, of the Eastern Area Roads Policing Unit, said: “I would urge anyone who witnessed this collision to call the Eastern Area Roads Policing Unit on 101 asking for myself as investigating officer.”
Motorists were caught in tailbacks after the incident, which caused severe delays on the roads.
The roads closures that were originally put in place were lifted at 11.20am.