It visits a different area of the city each week to make it easier for people to have the vaccine, while experts are also on hand any queries about the vaccination programme.
Anyone who is aged 18 or over can now visit the bus to get their first jab, including those who are not registered with a GP or do not have an NHS number.
Those who had their first dose at least eight weeks ago can also attend today's session in Holbeck as the 'Grab a Jab' campaign comes to an end.
Where will the bus be each week?
The sessions take place between 10am and 3pm on a drop-in basis.
June 29-July 2: Meynell Approach, Adjacent to St Matthew’s Church, Holbeck, LS11 9PZ.
July 5-9: South Seacroft One Stop Centre, Moresdale Lane, Leeds, LS14 6GG.
July 5-9: Kentmere Community Centre, Kentmere Avenue, Seacroft, Leeds, LS14 1BW.
July 12-16: Oblong Community Centre, Leeds, LS6 2NY.
July 20-23: CATCH (next to Hovingham Primary School), ARK, Hovingham Avenue, Harehills, Leeds, LS8 3QY.
July 27-30: Leeds Grand Mosque, 9 Woodsley Road, Woodhouse, Leeds, LS6 1SN.
August 3-6: BAME Health & Wellbeing Hub (formerly known as the Fredrick Hurdle Centre), Reginald Terrace, Leeds, LS7 3EZ.