The pubs will be open from 9am to 9pm from Sunday to Thursday and 9am to 10pm on Fridays and Saturdays, although some will have restrictions on closing times.
They will offer a slightly reduced menu, with food available from 9am to 8pm seven days a week.
Customers will be able to order and pay through the Wetherspoon app, and staff will be able to take orders and payment at the table.
Every new shop and restaurant at White Rose Shopping Centre plus two more arrivals on the way
Analysis suggests Leeds United supporters are set to lose out due to surging fuel costs
Harrogate anger over plans to build multi-use conference centre in Leeds
Discount store offering 4,000 products for £1 and under to open in Leeds city centre
'Popular and high-earning' Garforth post office is up for sale
The pubs will not be operating a booking system.
Customers will be able to enter the pubs to gain access to the outside areas and use toilets, while test and trace will be in operation and hand sanitisers will be available.
There are four Wetherspoon pubs in Leeds city centre - The Cuthbert Brodrick in Portland Crescent, Becketts Bank in Park Row, The Hedley Verity in Woodhuse Lane and the Wetherspoons in Leeds Station.
The pub-chain also has branches in Bramley, Cross Gates, Morley, Pudsey, Garforth, Yeadon and Otley.
Wetherspoon chief executive John Hutson said: “We are looking forward to welcoming our customers and staff back to our pubs.”
Pubs and restaurants in England will be able to serve customers outdoors from April 12 as part of the road map out of the lockdown which has devastated the hospitality sector.
Wetherspoon has 875 pubs in the UK, including 750 in England.