Adele has won five Grammys on a record-breaking night for the British star, but she was left "devastated" after fluffing her musical tribute to George Michael.
The 28-year-old singer won album of the year for 25 and record and song of the year for Hello, beating her "idol" Beyonce to the three top awards.
A tearful Adele dedicated her album award to Beyonce, who missed out with her celebrated visual record Lemonade.
"I can't possibly accept this award," she said.
"I'm very humble and I'm grateful and gracious but my artist of my life is Beyonce and the Lemonade album was just so monumental - Beyonce, it was so monumental - and so well thought out and so beautiful and soul-bearing.
"All us artists here, we f****** adore you.
"The way you make me and my friends feel. The way you make my black friends feel is empowering. You make them stand up for themselves and I love you and I always have."
She added: "My idol is Queen Bey and I adore you."
Adele also won best pop vocal album for 25 and best pop solo performance for Hello, taking her total number of Grammy wins to 15.
She is the first artist to win song, record and album of the year in the same year twice following her success in 2012 with her album 21 and single Rolling In The Deep.
Adele had earlier been left in tears during the star-studded ceremony in Los Angeles after she restarted her rendition of Michael's song Fast Love.
She swore as she called a halt to her performance, telling the audience: "I'm sorry, I can't mess this up for him."
Backstage, Adele said she was "devastated" about restarting the song - a year after she struggled with sound problems during her performance at the 2016 Grammys.
There was more British success as David Bowie won four posthumous Grammys following his death from cancer last year.
Bowie, who died in January 2016 aged 69, won best alternative music album, best rock performance and best engineered non-classical album for his last release, Blackstar.
He also won best rock song for his single Blackstar, while the Blackstar album won another Grammy when Jonathan Barnbrook took home best recording package for his artwork on the record.
Bowie's awards were his first music Grammys after previously winning best music video in 1985 for Jazzin' For Blue Jean and a lifetime achievement award in 2006.
Beyonce made her first public performance since announcing she is pregnant with twins as she performed two songs from her hit album Lemonade.
Her husband Jay Z and their daughter Blue Ivy were in the audience as she won best urban contemporary album and best music video for Formation.
On stage, Beyonce said the album was made to "give a voice to our pain" and to "confront issues that make us uncomfortable".
Chance The Rapper won best new artist, best rap album and best rap performance after becoming the first artist to be nominated for a streaming-only album following the release of Coloring Book.
Described by organisers as music's biggest night, stars including Kanye West, Justin Bieber and Drake - who won two awards for Hotline Bling - did not attend the ceremony.
Rapper Busta Rhymes took aim at US president Donald Trump as he performed with A Tribe Called Quest.
On stage, he said: "I just want to thank President Agent Orange for perpetuating all of the evil that you've been perpetuating throughout the United States.
"I want to thank President Agent Orange for his unsuccessful attempt at the Muslim ban."
The two members of Twenty One Pilots removed their trousers as they took to the stage to collect the award for best pop duo/group performance.
Lead singer Tyler Joseph said his bandmate Josh Dun had suggested the stunt while they watched the Grammys years before they were famous.
There were more sound problems during the ceremony as Metallica and Lady Gaga performed Moth Into Flame together.
The microphone used by the band's frontman James Hetfield was not working at the start of the performance, forcing him to share Gaga's microphone.
Bruno Mars performed Let's Go Crazy in a tribute to Prince, following his sudden death in April last year
Bee Gees star Barry Gibb was in audience as singers including Demi Lovato and Tori Kelly performed a medley of the band's hits to celebrate the 40th anniversary of the Saturday Night Fever soundtrack.
British comedian James Corden hosted the awards show and recreated his popular Carpool Karaoke sketch, singing Sweet Caroline with a host of famous singers.
Album Of The Year Adele - 25
Record Of The Year Adele - Hello
Song Of The Year Adele - Hello
Best New Artist Chance The Rapper
Best Pop Vocal Album Adele - 25
Best Pop Solo Performance Adele - Hello
Best Pop Duo/Group Performance Twenty One Pilots - Stressed Out
Best Dance Recording The Chainsmokers featuring Daya - Don't Let Me Down
Best Dance/Electronic Album Flume - Skin - Flume
Best Rock Performance David Bowie - Blackstar
Best Rock Song David Bowie - Blackstar
Best Rock Album Cage The Elephant - Tell Me I'm Pretty
Best Alternative Music Album David Bowie - Blackstar
Best R&B Performance Solange - Cranes in the Sky
Best R&B Song Maxwell - Lake By The Ocean
Best Urban Contemporary Album Beyonce - Lemonade
Best R&B Album Lalah Hathaway - Lalah Hathaway Live
Best Rap Performance Chance The Rapper Featuring Lil Wayne & 2 Chainz - No Problem
Best Rap/Sung Performance Drake - Hotline Bling
Best Rap Song Drake - Hotline Bling
Best Rap Album Chance The Rapper - Coloring Book
Best Song Written For Visual Media Justin Timberlake - Can't Stop The Feeling
Best Recording Package Jonathan Barnbrook, art director on David Bowie's Blackstar
Best Engineered Album, Non-Classical David Bowie - Blackstar
Producer Of The Year, Non-Classical Greg Kurstin
Best Music Video Beyonce - Formation
Best Music Film The Beatles: Eight Days A Week - The Touring Years