Rhinos have won their last two matches, but five players are in contention after injury and two will return from suspension.
The pack effectively picks itself, with prop Zane Tetevano and second-rower James Bentley likely to return in a straight swap for Matt Prior and Morgan Gannon who drop out because of suspension.
But the situation in the backs is more tricky. Here's how Leeds could line up.
1. Richie Myler (full-back)
Might go into the halves on his return from injury, but has played his best rugby for Leeds at full-back.
Photo: Tony Johnson
2. David Fusitu'a (wing)
Available after two months out following knee surgery, is one of only two specialist wingers in the 21.
Photo: Allan McKenzie/SWpix.com
3. Jack Broadbent (centre)
Has gone well at full-back, but Smith may feel it's time to give youngster Max Simpson a rest from first team action, in which case Broadbent will presumably slot in there.
Photo: Bruce Rollinson
4. Zak Hardaker (centre)
With Harry Newman and Liam Sutcliffe ruled out, Hardaker will give Leeds valuable experience in the three-quarters in his first game for them since 2016.
Photo: Phil Daly/Leeds Rhinos/SWpix.com