An impressive display from Leeds Medics saw them put together a huge 8-2 victory against Wigton Moor in the only game in the Premier League.
Brad Chambers scored a hat-trick and his goals were added to by John Forrest and Hugh Goodfield, who scored two apiece.
David Ashmore also scored for Medics.
In the Championship, Alwoodley Reserves climbed to the top of the table with a 6-1 win against Collingham Juniors OB.
Alwoodley scorers included Ajmal Abrar, Carl Hasty and Matt Conn, while Dan Whincup was the pick of the players in front of goal for Alwoodley, hitting a brace.
St Nicholas climbed to second after beating Batelians 4-2.
St Nicholas’s goals came from a Mark Hill double and strikes from Paul Hewson and Ryan Brough.
Nathan Hallas and Mathew Bolton scored for Batelians.
Beeston St Anthony’s undefeated start to the season was ended by Leeds Medics Reserves, who beat them 4-2.
Sverrir Kristinsson was the hero for Medics, scoring twice in the last 10 minutes to give them the three points.
Tony Garth put Beeston into a 2-1 lead with two goals, but Medics could rely on goals from Alan Salter and Kieran Wardman.
Beeston Juniors could manage only a 3-3 draw against Thornesians.
Jamie Mitchell scored twice for Juniors, with Paul Tierney also scoring, while Joe Cook, Liam Devlin and James Wootton all bagged for Thornesians to earn their first points of the season.
Leeds Independent are still seeking their first win after a 2-2 draw with Morley Town.
Gavin Hercules and Marlon Richards put Independent ahead, but a brace from Danny Holland meant the two sides shared the spoils.
Drighlington remain on top of Division 1 after a 2-2 draw against Wortley.
Sam Thorpe and Shane Sowden put the home side ahead, but Wortley equalised to earn the draw.
Calverley United won 3-1 against Colton Athletic, who went ahead in the game through a Sam Rudd header.
Ben Waller equalised for United, who went ahead through Tom Westerton. Ben Binns then rounded off the win.
Wheelwright OB thrashed Grangefield OB Reserves 8-1, with Johnny Beverley and Daz Fothergill scoring four apiece.
Jordan Northin scored a brace, and Jamal Nash and Andrew Scullion scored one each for St. Bedes as they drew 4-4 with Dewsbury Rangers.
Garforth Rangers also beat Rothwell Reserves 1-0.