Ahead of kick-off, we've taken a look back at the last time the Whites triumphed over the Reds back in 2001 - a Premier League classic that saw David O'Leary's side hang on to claim a precious win at Anfield with a 2-1. Here's where every player in the starting XI - from both sides - is now.
7. Stephane Henchoz - Liverpool - CB
After hanging up his boots at Blackburn in 2018, the defender embarked upon a coaching career. He began with Rovers' youth side, and is now at the helm Neuchatel Xamax FCS in his native Switzerland. Photo: Gary M. Prior
8. Dominic Matteo - Leeds United - CB
Matteo worked briefly as a football ambassador for Leeds in 2013. Recently, he battled with a brain tumour, but rallied to be declared as recovered earlier this year. Photo: Jamie McDonald
9. Ian Harte - Leeds United - LB
The set-piece sensation left the Whites in 2004, and was a second-tier champion with Reading in 2012. He's now a football agent. Photo: Charles McQuillan
10. Markus Babbel - Liverpool - LB
After retiring from playing the game, Babbel took the reins at VfB Stuttgart following a stint as their assistant manager. He was last in charge of Western Sydney Wanderers, but was sacked last January. Photo: Hagen Hopkins
11. Lee Bowyer - Leeds United - RW
Bowyer went on to earn an England call-up the following year, and later played for the likes of Newcastle United and West Ham. He's now the manager of League One side Charlton Athletic. Photo: Catherine Ivill
12. Danny Murphy - Liverpool - RW
The ex-England international was a Europa League runner-up with Fulham in 2010, and finished his career with Blackburn. He's now a pundit for BBC Sport. Photo: Alex Livesey