The Whites will be looking to kick-off May with another positive result after going unbeaten in the top flight throughout April.
Leeds saw wins over Sheffield United and Manchester City followed up by draws against Liverpool and Manchester United - and are now firmly safe for next season.
Bielsa's men travel to relegation-threatened Brighton this weekend - though they do have a seven-point cushion over Fulham who head up the drop zone.
United will be without defender and club captain Liam Cooper, who serves the final match of a three-game ban for a straight red card.
Star winger Raphinha is also missing due to a thigh issue but attacker and record signing Rodrigo will be welcomed back after a spell on the sidelines thanks to a muscle injury.
There is another doubt over wide man Helder Costa after he limped off last week, though Bielsa remained coy over his inclusion.
Here, the Yorkshire Evening Post pick out our line-up for the trip to the Amex stadium on Saturday afternoon:
1. Meslier - GK
Bielsa's number one and what an impressive season he is having. Photo: Getty
2. Ayling - RWB
His final game as stand-in skipper should Cooper return next week. Has really shone on the right side of defence this season. Photo: Getty
3. Llorente - CB
Great to see him finally get a run of games after his injury woes and he's showing why Leeds were so keen on his services last summer. Photo: Getty
4. Struijk - CB
What a campaign he is having for his first full year of senior involvement. Solid whenever called upon. Photo: Getty
5. Alioski - LWB
Has arguably been in his best form of the season in recent weeks. Photo: Getty
6. Phillips - CDM
The key cog in the machine. Was fantastic last weekend up against Bruno Fernandes. Photo: Getty