Leeds United head into the break 1-0 down at Craven Cottage with midfielder Kevin McDonald handing Fulham a half-time lead.
The first chance of the opening half fell to Stuart Dallas after just a minute with the Northern Irishman blazing over the bar from just inside the area.
Three minutes later and it was Fulham's turn, winger Matt Targett got in behind on the left flank and picked out loanee Aleksandar Mitrovic but he could only drag his effort wide.
The hosts should have been ahead on the 10 minute mark as Ryan Sessegnon again exposed the Whites on the left to pick out Floyd Ayite who smashed his thunderous effort against the post.
Leeds cleared and it was Mitrovic who was there again just moments later to meet the resulting corner, but Whites stopper Bailey Peacock-Farrell was equal to the effort.
Fulham surged forward once more and Stefan Johansen scuffed another dangerous Ayite cross before the United back line blocked the resulting scramble away for a corner.
The hosts finally had their breakthrough with the following set-piece as Mitrovic once again caused mayhem meeting the corner with another powerful header.
His effort hit Kevin McDonald and wrong footed Peacock-Farrell in the Leeds goal as it agonisingly crept into the bottom corner.
The home crowd were spurred on by the opening goal but it was actually Leeds who finished the half strongest following the early storm of pressure.
Samuel Saiz fed through fellow Spaniard Pablo Hernandez but he couldn't quite get a shot away before he returned the favour just minutes later.
This time Saiz was flagged for offside as the referee signalled for the break.