The sixth-placed Whites were around 6-5 to beat Jaap Stam’s third-placed Royals on Tuesday when Reading arrived at Elland Road having won five of their last six league games.
A Chris Wood strike and Souleymane Doukara penalty sent Stam’s men packing 2-0 but Leeds are now even bigger odds to beat Saturday’s 14th-placed visitors Brentford.
The Bees are chasing a quick-hat trick of victories with Saturday’s 2-1 win at home to Burton Albion followed by a 1-0 success on Tuesday night at Bristol City.
Brentford have recorded three away wins already in the league this season - at high-flying Brighton back in September, as well as at QPR in October and then Tuesday night’s success in Bristol.
Dean Smith’s side are 51-20 with Marathon Bet to bag a fourth away win of the season at Elland Road while the draw is on offer at 5-2.
Leeds, though, have picked up 19 points out of a last possible 24 at Elland Road and can be backed at 5-4 - though the Whites will have to sink the Bees without the services of top scorer Chris Wood who picked a hamstring injury in Tuesday’s win against Reading.
Consequently, Brentford’s top scorer Scott Hogan - who already has 13 goals for the current campaign - is 5-1 to net first.
United’s Kemar Roofe is next in the list at 13-2, ahead of Marcus Antonsson at 13-2 and teen striker Mallik Wilks who is the same price.
Souleymane Doukara looks a good price at 7s, just ahead of Brentford’s Lasse Vibe and Philipp Hofmann at 8s.
Alex Mowatt is 10s, the same price as no goalscorer and Brentford’s Romaine Sawyers.
Hadi Sacko is 11-1 while Stuart Dallas might get a bit of interest 14s.
A 1-1 draw is rated the most likely score outcome at 13-2, just ahead of a 1-0 win for Leeds at 15-2.