The crash happened near the Broadway and New Road Side roundabout in the Horsforth area of the city.
Traffic is reported to be queuing on a number of surrounding routes.
Bus operator First has warned passengers to expect delays to its services.
Road accident triggers rush-hour disruption for motorists in Leeds
Drivers are facing lengthy rush-hour delays in Leeds this morning after a road accident.
By The Newsroom
Tuesday, 7th November 2017, 7:37 am
Updated Tuesday, 12th December 2017, 5:27 am