Among those taking part on behalf of Leeds Children’s Hospital is three-year-old Mia Mason from Harrogate.
The youngster was born with congenital nephrotic syndrome and had a lifesaving kidney transplant at the hospital in Leeds last year.
And now Mia is planning to compete in three events to raise money to support the hospital’s work.
Her family and friends have so far raised £25,000 to support the transplant and dialysis wards, some of which will go towards Little Livers, the hospital charity that supports the children’s transplant team.
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The Leeds children’s team will be one of the biggest at the games and is hoping to win an array of medals at the three day annual event which was officially opened yesterday.
Celia McKenzie, matron at Leeds Children’s Hospital, said: “The Games are always a very special event for our transplant youngsters and their families - there is a fantastic team spirit and everyone has great fun.
“It is great for them meet up with others who have had transplants here in Leeds and right across the country and celebrate the new lease of life an organ transplant gives.
The Yorkshire Evening Post is backing Leeds Teaching Hospital NHS Trust’s Be A Hero campaign in a bid to boost organ donation in the region.
To support the campaign visit www.leedsth.nhs.uk/be-a-hero.