Leeds have been boosted by the news that head coach Marcelo Bielsa has signed a new one-year deal on the eve of the clash and the 65-year-old Argentinian has no new injury problems to contend with.
The YEP's Lee Sobot takes a look at a predicted line up.
1. Illan Meslier (GK)
Looks all set to start the season as first choice 'keeper after his excellent finish to United's promotion winning campaign with seven clean sheets in his last ten games. Photo by Michael Regan/Getty Images.
2. Luke Ayling (RB)
The signing of Robin Koch and positive reports from Marcelo Bielsa about Koch's fitness would seem to indicate that Ayling will be lining up in his natural position of right back. Photo by Michael Regan/Getty Images.
3. Liam Cooper (CB)
What will be a very proud moment for the Leeds skipper who will lead United out at Anfield as captain upon the club's Premier League return but most likely with a new defensive partner at centre-back. Photo by Michael Regan/Getty Images.
4. Robin Koch (CB)
Bielsa often takes a patient approach with new signings given his fitness demands but Koch is in "a very good physical condition" and there must be every chance of the German slotting straight in next to Cooper at centre-back. Picture by LUFC.
5. Stuart Dallas (LB)
Dallas seems capable of playing just about anywhere but the Northern Ireland international made the left back slot his own last season and seems likely to start there against the Reds. Photo by Michael Regan/Getty Images.
6. Kalvin Phillips (CDM)
United's England international after his Three Lions debut against Denmark in midweek and will surely be in the holding midfield role in which he has become affectionately known as the Yorkshire Pirlo. Photo by Michael Regan/Getty Images.