HOLDERS LEEDS Rhinos will begin their attempt to win the Ladbrokes Challenge Cup for a third straight year away to Huddersfield Giants - who were the last team to beat them in the competition.
Rhinos were defeated 24-8 at Huddersfield in a fifth round tie in May, 2013, but went on to lift the trophy at Wembley in 2014 and 2015.
They began last year’s campaign with a 48-16 home win over Huddersfield.
The sixth round tie will be played over the weekend of May 6-8, meaning successive trips to John Smith’s Stadium for Leeds, who go there in First Utility Super League on Friday, April 29.
Castleford Tigers and Hull are also involved in all-Super League ties.
Tigers have home advantage against Salford Red Devils, who won 32-16 at the Jungle in March.
Hull travel to St Helens, where they won 17-16 earlier this month.
Wakefield Trinity Wildcats will be at home to Kingstone Press League One newcomers Toulouse, who are the lowest-ranked team left in the competition.
Also welcoming French opposition will be Batley Bulldogs, who play host to Catalans Dragons.
Halifax play host to Widnes Vikings and Dewsbury Rams will be at home to Wigan Warriors for the second time in three seasons.
The full draw is: Castleford Tigers v Salford Red Devils, Oldham v Warrington Wolves, Dewsbury Rams v Wigan Warriors, Batley Bulldogs v Catalans Dragons, Halifax v Widnes, St Helens v Hull, Huddersfield Giants v Leeds Rhinos, Wakefield Trinity Wildcats v Toulouse Olympique.