Manchester United and Chelsea will face each other in the Champions League quarter-finals after being drawn in a rematch of their 2008 European final.
Premier League leaders United, who beat the Blues on penalties in Moscow three years ago, will enjoy home advantage in the second leg against the defending English league champions.
Tottenham were handed a glamorous but daunting clash against Real Madrid. However, they will take on the Spanish giants at White Hart Lane in the second match.
Favourites Barcelona, who conquered Arsenal in the last round, were handed one of the two supposedly easier draws and will take on Ukrainians Shakhtar Donetsk while defending champions Inter Milan will face German side Schalke 04.
The semi-finals were also drawn today and the winner of the Chelsea-United clash will meet Inter or Schalke in the last four, with the winning English side at home second.
Should Spurs come through against Madrid, they will be at home first against Barca or Shakhtar.
The semi-final first legs take place on April 26 and 27 with the second legs on May 3 and 4, with the final at Wembley on Saturday, May 28.
Should they beat Schalke, Inter would represent a tough test in the last four for Chelsea or United. While they are without Mourinho, who led them to glory in the tournament last season, they are back in form since Leonardo replaced Rafael Benitez recently.
Schalke this week sacked Felix Magath despite his significant achievement in guiding them to this stage, appointing former Hoffenheim boss Ralf Rangnick as his successor.
Shakhtar are perennial Champions League stalwarts and are not to be taken lightly, especially as favourites Barca have injury problems as well as a Spanish league title race and domestic cup final to contend with.